The Quixotic Method
AI, biology, philosophy, and better technical judgment.Between the windmill and the brick.
Writing
Essays and notes from the side of the work.
The Quixotic Method is where I write about AI, biology, philosophy, and the technical questions I want to think through in public.
Recent posts appear here alongside links to the full archive on Substack.
AI in Clinical Trials: Stop Talking About “Replacement”
Why the real battle is not over simulating patients, but over deciding what a patient 'is' for the purpose of evidence
Longevity, CES 2026, and the War for Your Biological Data
My opinions on the future of the Quantified Self industry
Why AGI is (fundamentally) dangerous
A brief snapshot of pre-AGI worries
Why We Think the Way We Think: On Prediction, Intuition, and the Limits of Rationality
Three showers worth of shower thoughts transcribed
Bots, Pathos, and the Epistemic Tightrope
What Reddit’s unauthorized AI experiment shows—and what it can’t show—about emotion’s place in reasoning.
First Principles Thinking
A philosophical extension to the 'First Principles' concept that led to SpaceX