Why it mattered
Protein design becomes more compelling when the generation step is matched with a validation story and a practical research workflow.
Protein design
De Novo Protein Binder Design
An RFdiffusion-based pipeline for generating and validating protein binders around active site motifs.
Connected generative structure design to validation workflows instead of stopping at novelty.
What I built
A pipeline that proposes structures conditioned on motifs, checks structural alignment, and estimates binding quality through downstream scoring.
What I learned
Generative biology is most interesting at the seam between model possibility and experimental plausibility.
More work